Competent Cell Product Comparison

NEB provides the following guide to ordering NEB competent cells by aligning our strains with the names of their counterparts from other suppliers.

Strain Name Company Catalog # Unit Size NEB Strain Name NEB # Unit Size
96 pack Gold Competent Cells** Agilent 200324 4 x 96-well plates NEB 5-alpha C2987 1 x 96-well plate
XL1-Blue MR Supercompetent Cells Agilent 200229 5 x 0.2ml NEB 10-beta Competent E.coli C3019 6 x 0.2ml
XL1-Blue Supercompetent Cells Agilent 200236 5 x 0.2ml NEB 5-alpha F´Iq Competent E.coli C2992 6 x 0.2ml
XL10-Gold Ultracompetent Cells Agilent 200314 5 x 0.1ml NEB Stable Competent E. coli (High Efficiency) C3040 6 x 0.2ml
SCS110 Competent Cells Agilent 200247 5 x 0.2ml dam-/dcm- Competent E.coli C2925 6 x 0.2ml
BL21 Competent Cells Agilent 200133 5 x 0.2ml BL21 Competent E.coli C2530 20 x 0.05ml
BL21(DE3) Competent Cells Agilent 200131 5 x 0.2ml BL21(DE3) Competent E.coli C2527 6 x 0.2ml
Agilent SURE2 Competent Cells Agilent 200152 10 x 0.10ml NEB Stable Competent E. coli (High Efficiency) C3040 20 x 0.05ml
XL1-Blue MRF’ Supercompetent Cells Agilent 200230 5 x 0.2 mL NEB® Stable Competent E. coli (High Efficiency) C3040 6 x 0.2 mL
BL21(DE3)pLysS Competent Cells Agilent 200132 5 x 0.2 mL T7 Express lysY Competent E. coli (High Efficiency) C3010 6 x 0.2 mL
E. cloni® 5-alpha Chemically Competent Cells† Lucigen 60602-2 12 x 0.1ml NEB 5-alpha Competent E. coli (High Efficiency) C2987 20 x 0.05ml
E. cloni® 10G CLASSIC Electrocompetent Lucigen 60117-1 24 reactions NEB 10-beta Electrocompetent E. coli C3020 6 x 0.1ml
E. cloni® 10G ELITE Electrocompetent Cells Lucigen 60052-1 12 reactions NEB 10-beta Electrocompetent E. coli C3020 6 x 0.1ml
E. cloni® 10G SUPREME Electrocompetent Cells Lucigen 60080-1 12 reactions NEB 10-beta Electrocompetent E. coli C3020 6 x 0.1ml
E. cloni® 10G Chemically Competent Cells Lucigen 60106-2 24 reactions NEB 10-beta Competent E. coli (High Efficiency) C3019 20 x 0.05ml
E. cloni® EXPRESS BL21(DE3) Chemically Competent Cells (=1 × 107 cfu/µg) Lucigen 60401-2 24 reactions BL21(DE3) Competent E. coli C2527 20 x 0.05ml
OverExpress C41 Chemically Competent Lucigen 60442-1 12 reactions Lemo21(DE3) Competent E. coli C2528 6 x 0.05ml
OverExpress C43 Chemically Competent Lucigen 60446-1 12 reactions Lemo21(DE3) Competent E. coli C2528 6 x 0.05ml
OverExpress C43(DE3) pLysS Chemically Competent Cells Lucigen 60448-1 12 x 0.05 mL Lemo21(DE3) Competent E. coli C2528 12 x 0.05 mL
OverExpress C41(DE3) pLysS Chemically Competent Cells Lucigen 60444-1 12 x 0.05 mL Lemo21(DE3) Competent E. coli C2528 12 x 0.05 mL
Endura Competent Cells (SOLO) Lucigen 60241-2 24 x 0.04 mL NEB® Stable Competent E. coli (High Efficiency) C3040H 20 x 0.05 mL
Endura Competent Cells (DUO) Lucigen 60240-2 12 x 0.08 mL NEB® Stable Competent E. coli (High Efficiency) C3040I 6 x 0.2 mL
HI-ControlTM BL21(DE3) Lucigen 60435-1 12 x 0.04 mL T7 Express lysY/Iq Competent E. coli (High Efficiency) C3013 6 x 0.2 mL
OverExpress C41(DE3) Chemically Competent Cells Millipore Sigma (Novagen) CMC0017  20 x 0.04 mL Lemo21(DE3) Competent E. coli C2528 12 x 0.05 mL
OverExpress C41(DE3) pLysS Chemically Competent Cells Millipore Sigma (Novagen) CMC0018  20 x 0.04 mL Lemo21(DE3) Competent E. coli C2528 12 x 0.05 mL
OverExpress C43(DE3) Chemically Competent Millipore Sigma (Novagen) CMC0019  20 x 0.04 mL Lemo21(DE3) Competent E. coli C2528 12 x 0.05 mL
OverExpress C43(DE3) pLysS Chemically Competent Cells Millipore Sigma (Novagen) CMC0020  20 x 0.04 mL Lemo21(DE3) Competent E. coli C2528 12 x 0.05 mL
SIG10 5a Chemically Competent Cells Millipore Sigma (Novagen) CMC0007 20 x 0.04 mL NEB 5-alpha Competent E. coli (High Efficiency) C2987 20 x 0.05ml
Veggie BL21(DE3) Singles Competent Cells Millipore Sigma (Novagen) 71252-4 22 reactions BL21(DE3) Competent E. coli C2527 20 x 0.05ml
Origami B Competent Cells Millipore Sigma (Novagen) 70836-3 0.4ml SHuffle® Express Competent E. coli C3028 6 x 0.05ml
Origami B(DE3) Competent Cells Millipore Sigma (Novagen) 70837-3 0.4ml SHuffle® T7 Express Competent E. coli C3029 6 x 0.05ml
Origami B(DE3)pLysS Competent Cells  Millipore Sigma (Novagen) 70839-3 0.4ml SHuffle® T7 Express lysY Competent E. coli C3030 6 x 0.05ml
Origami 2(DE3) Competent Cells Millipore Sigma (Novagen) 71345-3 0.4ml SHuffle® T7 Competent E. coli C3026 6 x 0.05ml
Origami 2(DE3) Singles Competent Cells  Millipore Sigma (Novagen) 71408-3 11 reactions SHuffle® T7 Competent E. coli C3026 6 x 0.05ml
BL21 Competent Cells Millipore Sigma (Novagen) 69449-4 1ml BL21 Competent E. coli C2530 20 x 0.05ml
BL21(DE3) Competent Cells Millipore Sigma (Novagen) 69450-4 1ml BL21(DE3) Competent E. coli C2527 20 x 0.05ml
BL21(DE3)pLysS Competent Cells Millipore Sigma (Novagen) 69451-4 1ml T7 Express lysY Competent E. coli (High Efficiency) C3010 20 x 0.05ml
NovaBlue Singles Competent Cells Millipore Sigma (Novagen) 70181-4 0.05 mL NEB® 5-alpha F'Iq Competent E. coli (High Efficiency) C2992H 20 x 0.05 mL
ElectroMAX DH10B T1 Phage-Resistant Competent Cells ThermoFisher (Invitrogen) 12033-015 5 x 0.1ml NEB 10-beta Electrocompetent E. coli C3020 6 x 0.1ml
ElectroMAX DH5α-E Cells* ThermoFisher (Invitrogen) 11319-019 5 x 0.1ml NEB 10-beta Electrocompetent E. coli C3020 6 x 0.1ml
MAX Efficiency® DH10B Competent Cells* ThermoFisher (Invitrogen) 18297-010 5 x 0.2ml NEB 10-beta Competent E. coli (High Efficiency) C3019 6 x 0.2ml
One Shot® TOP10 Chemically Competent E. coli ThermoFisher (Invitrogen) C4040-03 20 x 0.05ml NEB 10-beta Competent E. coli (High Efficiency) C3019 20 x 0.05ml
One Shot® MAX Efficiency DH10B T1 Phage Resistant Cells   ThermoFisher (Invitrogen) 12331-013 20 x 0.05ml NEB 10-beta Competent E. coli (High Efficiency) C3019 20 x 0.05ml
One Shot® MAX Efficiency® DH5α-T1R Competent Cells   ThermoFisher (Invitrogen) 12297-016 20 x 0.05ml NEB 5-alpha Competent E. coli (High Efficiency) C2987 20 x 0.05ml
MAX Efficiency® DH5α T1 Phage Resistant Competent Cells   ThermoFisher (Invitrogen) 12034-013 1ml NEB 5-alpha Competent E. coli (High Efficiency) C2987 6 x 0.2ml
Subcloning Efficiency DH5α Competent Cells* ThermoFisher (Invitrogen) 18265-017 4 x 0.5ml NEB 5-alpha Competent E. coli (Subcloning Efficiency) C2988 6 x 0.4ml
MAX Efficiency® DH5αF'IQ Competent Cells*  ThermoFisher (Invitrogen) 18288-019 5 x 0.2ml NEB 5-alpha F´Iq Competent E. coli (High Efficiency) C2992 6 x 0.2ml
One Shot® Mach1 T1 Phage-Resistant Chemically Competent E. coli  ThermoFisher (Invitrogen) C8620-03 20 x 0.05ml NEB Turbo Competent E. coli (High Efficiency) C2984 20 x 0.05ml
One Shot® BL21(DE3) Chemically Competent E. coli  ThermoFisher (Invitrogen) C6000-03 20 x 0.05ml BL21(DE3) Competent E. coli C2527 20 x 0.05ml
One Shot® BL21(DE3)pLysS Chemically Competent E. coli  ThermoFisher (Invitrogen) C6060-03 20 x 0.05ml T7 Express lysY Competent E. coli (High Efficiency) C3010 20 x 0.05ml
One Shot® Stbl3 Chemically Competent E. coli ThermoFisher (Invitrogen) C7373-03 20 x 0.05ml NEB Stable Competent E. coli (High Efficiency) C3040 20 x 0.05ml
Mix & Go Competent Cells - Strain DH5 Alpha Zymo T3007 10 x 0.1 mL NEB® 5-alpha Competent E. coli (High Efficiency) C2987I 6 x 0.2 mL
Mix & Go Competent Cells - Strain Zymo 10B Zymo T3019 10 x 0.1 mL NEB® 10-beta Competent E. coli (High Efficiency) C3019I 6 x 0.2 mL

* These strains are not phage resistant. All NEB competent cells are phage resistant.
** Note that this product has a TE of > 1 x 108, whereas NEB C2987 has a TE of 1-3 x 109
† Note Lucigen 6060-2 has a TE of ≥ 1x108, whereas NEB C2987 has a TE of 1-3x109
†† For large plasmids, choose C3019, NEB 10-beta Competent E. coli (High Efficiency)

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