Competent Cell Product Comparison

NEB provides the following guide to ordering NEB competent cells by aligning our strains with the names of their counterparts from other suppliers.

Strain Name Company Catalog # Unit Size NEB Strain Name NEB # Unit Size
GC5™ Competent Cells** Sigma G7419 1 x 96-well plate NEB 5-alpha C2987 1 x 96-well plate
BL21-T1R Competent Cells Sigma B2685 10 x 0.05ml BL21 Competent E. coli C2530 20 x 0.05ml
BL21(DE3)-T1R Sigma B2935 10 x 0.05ml BL21(DE3) Competent E. coli C2527 20 x 0.05ml
BL21(DE3)pLysS-T1R Sigma B3310 10 x 0.05ml T7 Express lysY Competent E. coli (High Efficiency) C3010 20 x 0.05ml
ElectroMAX™ DH10B™ T1 Phage-Resistant Competent Cells Invitrogen 12033-015 5 x 0.1ml NEB 10-beta Electrocompetent E. coli C3020 6 x 0.1ml
ElectroMAX™ DH5α-E™ Cells* Invitrogen 11319-019 5 x 0.1ml NEB 5-alpha Electrocompetent E. coli C2989 6 x 0.1ml
MAX Efficiency® DH10B™ Competent Cells* Invitrogen 18297-010 5 x 0.2ml NEB 10-beta Competent E. coli (High Efficiency) C3019 6 x 0.2ml
One Shot® TOP10 Chemically Competent E. coli Invitrogen C4040-03 20 x 0.05ml NEB 10-beta Competent E. coli (High Efficiency) C3019 20 x 0.05ml
One Shot® MAX Efficiency™ DH10B™ T1 Phage Resistant Cells   Invitrogen 12331-013 20 x 0.05ml NEB 10-beta Competent E. coli (High Efficiency) C3019 20 x 0.05ml
One Shot® MAX Efficiency® DH5α™-T1R Competent Cells   Invitrogen 12297-016 20 x 0.05ml NEB 5-alpha Competent E. coli (High Efficiency) C2987 20 x 0.05ml
MAX Efficiency® DH5α™ T1 Phage Resistant Competent Cells   Invitrogen 12034-013 1ml NEB 5-alpha Competent E. coli (High Efficiency) C2987 6 x 0.2ml
Subcloning Efficiency™ DH5α™ Competent Cells* Invitrogen 18265-017 4 x 0.5ml NEB 5-alpha Competent E. coli (Subcloning Efficiency) C2988 6 x 0.4ml
MAX Efficiency® DH5αF'IQ™ Competent Cells*  Invitrogen 18288-019 5 x 0.2ml NEB 5-alpha F´Iq Competent E. coli (High Efficiency) C2992 6 x 0.2ml
One Shot® Mach1™ T1 Phage-Resistant Chemically Competent E. coli  Invitrogen C8620-03 20 x 0.05ml NEB Turbo Competent E. coli (High Efficiency) C2984 20 x 0.05ml
BL21-AI™ One Shot® Chemically Competent E. coli   Invitrogen C6070-03 20 x 0.05ml Lemo21(DE3) Competent E. coli C2528 6 x 0.05ml
One Shot® BL21(DE3) Chemically Competent E. coli  Invitrogen C6000-03 20 x 0.05ml BL21(DE3) Competent E. coli C2527 20 x 0.05ml
One Shot® BL21(DE3)pLysS Chemically Competent E. coli  Invitrogen C6060-03 20 x 0.05ml T7 Express lysY Competent E. coli (High Efficiency) C3010 20 x 0.05ml
One Shot® BL21(DE3)pLysS Chemically Competent E. coli Invitrogen C6060-10 10 x 0.05ml T7 Express lysY Competent E. coli (High Efficiency) C3010 20 x 0.05ml
DH5alphaF'Iq** EMP4BIO 71011 1 x 96-well plate NEB 5-alpha C2987 1 x 96-well plate
Veggie™ BL21(DE3)pLysS Singles™ Competent Cells EMD4Biosciences 71253-4 22 reactions T7 Express lysY Competent E. coli (High Efficiency) C3010 20 x 0.05ml
Veggie™ BL21(DE3) Singles™ Competent Cells EMD4Biosciences 71252-4 22 reactions BL21(DE3) Competent E. coli C2527 20 x 0.05ml
Origami™ B Competent Cells EMD4Biosciences 70836-3 0.4ml SHuffle® Express Competent E. coli C3028 6 x 0.05ml
Origami™ B(DE3) Competent Cells EMD4Biosciences 70837-3 0.4ml SHuffle® T7 Express Competent E. coli C3029 6 x 0.05ml
Origami™ B(DE3)pLysS Competent Cells  EMD4Biosciences 70839-3 0.4ml SHuffle® T7 Express lysY Competent E. coli C3030 6 x 0.05ml
Origami™ 2(DE3) Competent Cells EMD4Biosciences 71345-3 0.4ml SHuffle® T7 Competent E. coli C3026 6 x 0.05ml
Origami™ 2(DE3) Singles™ Competent Cells  EMD4Biosciences 71408-3 11 reactions SHuffle® T7 Competent E. coli C3026 6 x 0.05ml
B834(DE3) Competent Cells EMD4Biosciences 69041-4 1ml T7 Express Crystal Competent E. coli (High Efficiency) C3022 20 x 0.05ml
BL21 Competent Cells EMD4Biosciences 69449-4 1ml BL21 Competent E. coli C2530 20 x 0.05ml
BL21(DE3) Competent Cells EMD4Biosciences 69450-4 1ml BL21(DE3) Competent E. coli C2527 20 x 0.05ml
BL21(DE3)pLysS Competent Cells EMD4Biosciences 69451-4 1ml T7 Express lysY Competent E. coli (High Efficiency) C3010 20 x 0.05ml
E. cloni® 5-alpha Chemically Competent Cells† Lucigen 60602-2 12 x 0.1ml NEB 5-alpha Competent E. coli (High Efficiency) C2987 20 x 0.05ml
E. cloni®10G BAC-Optimized Electrocompetent Lucigen 60215-1 10 reactions NEB 10-beta Electrocompetent E. coli C3020 6 x 0.1ml
E. cloni® 10G CLASSIC Electrocompetent Lucigen 60117-1 24 reactions NEB 10-beta Electrocompetent E. coli C3020 6 x 0.1ml
E. cloni® 10G ELITE Electrocompetent Cells Lucigen 60052-1 12 reactions NEB 10-beta Electrocompetent E. coli C3020 6 x 0.1ml
E. cloni® 10G SUPREME Electrocompetent Cells Lucigen 60080-1 12 reactions NEB 10-beta Electrocompetent E. coli C3020 6 x 0.1ml
E. cloni® 10G Chemically Competent Cells Lucigen 60106-2 24 reactions NEB 10-beta Competent E. coli (High Efficiency) C3019 20 x 0.05ml
E. cloni® EXPRESS BL21(DE3) Chemically Competent Cells (=1 × 107 cfu/µg) Lucigen 60401-2 24 reactions BL21(DE3) Competent E. coli C2527 20 x 0.05ml
OverExpress C41 Chemically Competent Lucigen 60442-1 12 reactions Lemo21(DE3) Competent E. coli C2528 6 x 0.05ml
OverExpress C43 Chemically Competent Lucigen 60446-1 12 reactions Lemo21(DE3) Competent E. coli C2528 6 x 0.05ml
Alpha-Select Bacteriophage T1-Resistant Gold Efficiency Bioline BIO-85030 20 x 0.05ml NEB 5-alpha Competent E. coli (High Efficiency) C2987 20 x 0.05ml
Alpha-Select Bronze Efficiency†† Bioline BIO-85025 10 x 0.2ml NEB 5-alpha Competent E. coli (Subcloning Efficiency) C2988 6 x 0.4ml
Alpha-Select Electrocompetent††† Bioline BIO-85028 10 x 0.1ml NEB 5-alpha Electrocompetent E. coli C2989 6 x 0.1ml
BIOBlue 109 Chemically Competent Cells* Bioline BIO-85037 20 x 0.05ml NEB 5-alpha F´Iq Competent E. coli (High Efficiency) C2992 20 x 0.05ml
CH3-Blue 109 Chemically Competent Cells* Bioline BIO-85040 20 x 0.05ml NEB 10-beta Competent E. coli (High Efficiency) C3019 20 x 0.05ml
dam- dcm- Bacteriophage T1-Resistant Bioline BIO-85044 10 x 0.1ml dam-/dcm- Competent E. coli C2925 20 x 0.05ml
96 pack Gold Competent Cells** Agilent/Stratagene 200324 4 x 96-well plates NEB 5-alpha C2987 1 x 96-well plate
XL1-Blue MR Supercompetent Cells Agilent/Stratagene 200229 5 x 0.2ml NEB 10-beta Competent E.coli C3019 6 x 0.2ml
XL1-Blue Supercompetent Cells Agilent/Stratagene 200236 5 x 0.2ml NEB 5-alpha F´Iq Competent E.coli C2992 6 x 0.2ml
XL10-Gold Ultracompetent Cells Agilent 200314 5 x 0.1ml NEB 5-alpha F´Iq Competent E.coli (High Efficiency) †††† C2992 6 x 0.2ml
SCS110 Competent Cells Agilent/Stratagene 200247 5 x 0.2ml dam-/dcm- Competent E.coli C2925 6 x 0.2ml
BL21 Competent Cells Agilent/Stratagene 200133 5 x 0.2ml BL21 Competent E.coli C2530 20 x 0.05ml
BL21(DE3) Competent Cells Agilent/Stratagene 200131 5 x 0.2ml BL21(DE3) Competent E.coli C2527 6 x 0.2ml
BL21(DE3)pLysS Competent Cells Agilent/Stratagene 200132 5 x 0.2ml T7 Express lysY Competent E.coli C3010 6 x 0.2ml
C-Max 5 Alpha Competent Cells BIO-RAD 170-3340 5 x 0.2ml NEB 5-alpha Competent E.coli C2987 6 x 0.2ml
C-Max 5 Alpha Competent Cells BIO-RAD 170-3342 10 x 0.05ml NEB 5-alpha Competent E.coli C2987 20 x 0.05ml
C-Max 5 Alpha F' Competent Cells BIO-RAD 170-3341 5 x 0.2ml NEB 5-alpha F´Iq Competent E.coli C2992 6 x 0.2ml
C-Max 5 Alpha F' Competent Cells BIO-RAD 170-3343 10 x 0.05ml NEB 5-alpha F´Iq Competent E.coli C2992 20 x 0.05ml
EP-Max™ 10B Electro-Competent Cells BIO-RAD 170-3330 5 x 0.1ml NEB 10-beta Electrocompetent E. coli C3020 6 x 0.1ml
BL21(DE3) Chemi-Competent Cells BIO-RAD 156-3003 10 x 0.05ml BL21(DE3) Competent E.coli C2527 20 x 0.05ml

* These strains are not phage resistant. All NEB competent cells are phage resistant.
** Note that this product has a TE of > 1 x 108, whereas NEB C2987 has a TE of 1-3 x 109
† Note Lucigen 6060-2 has a TE of ≥ 1x108, whereas NEB C2987 has a TE of 1-3x109
†† Note Bioline BIO-85025 has a TE of ≥ 107, whereas NEB C2988 has a TE of > 1x106
††† Note Bioline BIO-85028 has a TE of ≥ 109, whereas NEB C2989 has a TE of 1-3x1010
†††† For large plasmids, choose C3019, NEB 10-beta Competent E. coli (High Efficiency)

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