Protein Phosphatases & Kinases

A kinase is an enzyme that attaches a phosphate group to a protein. A phosphatase is an enzyme that removes a phosphate group from a protein. Together, these two families of enzymes act to modulate the activities of the proteins in a cell, often in response to external stimuli. A veritable red light/green light system, kinases generally turn a protein on, while a phosphatase turns the protein off.

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Protein Kinase Substrate Recognition

NEB offers protein kinases for a number of different specificity motifs. Within each recognition determinant, the phosphoacceptor residue is a serine, threonine or tyrosine.