FAQ: Why does the Nucleoside Digestion Mix freeze when stored at -20°C?

In order to reduce the ion suppression effects of glycerol during mass spectrometry analysis, the Nucleoside Digestion Mix has been formulated to contain very little glycerol (<1%) and therefore the mix will freeze when stored at -20°C. The mix is stable for >2 years when stored at -20°C and can withstand 50 freeze-thaw cycles without significant activity loss.